Found 9 matching trials
Tolcapone in Obsessive Compulsive Disorder
PHASE2The proposed study will consist of a 5-week double-blind cross-over study t...
Location
University of Chicago
Short-term Effects of TOLCAPONE on Transthyretin Stability in Subjects With Leptomeningeal TTR Amyloidosis (ATTR)
EARLY_PHASE1The purpose of this study is to determine whether Tolcapone crosses from th...
Location
Amyloidosis Center, Boston Medical Center
A Trial Evaluating Effects of COMT Inhibition in Patients With Acquired Brain Injury
PHASE2This is a follow-up study for an ongoing open label trial conducted by the ...
Location
Sheppard Pratt Health System
Pharmacokinetics of Levodopa/Carbidopa Infusion With and Without Oral Catechol-O-methyl Transferase (COMT) Inhibitors
PHASE4The purpose of this study is to determine whether oral intake of COMT inhib...
Location
Uppsala University Hospital
Effects of Cortical Dopamine Regulation on Drinking, Craving, and Cognitive Control
PHASE2The purpose of this study is to determine whether the catechol-O-methyltran...
Location
Medical University of South Carolina
Evaluation of Tolcapone as a Cognitive Enhancer in Schizophrenia
PHASE2Objective: To assess the efficacy of tolcapone to improve cognition in schi...
Location
Clinica Universidad de Navarra
Dopaminergic Mechanisms Underlying Human Social Behavior
EARLY_PHASE1Developing theoretical, quantitative models of the basic cognitive mechanis...
Location
University of California, Berkeley
COMT Inhibition Among Individuals With Comorbid AUD/ADHD
PHASE2The purpose of this study is to determine whether the catechol-O-methyltran...
Location
University of Colorado Anschutz Medical Campus
Effects of Tolcapone on Frontotemporal Dementia
PHASE2This study will test the effects of a medication called tolcapone on cognit...
Location
Columbia University Irving Medical Center